The Kennedy Neuroimaging of Aging and Cognition (KNAC) lab is directed by Dr. Kristen Kennedy at the University of Texas at Dallas' Center for Vital Longevity. Numerous factors influence the aging of the brain and in part determine how well we are able to age cognitively. The KNAC lab is interested in the neural, genetic and lifestyle factors that guide this process. Our research uses structural and functional neuroimaging techniques to investigate how the health of our brain's structure supports the brain's function and how these impact our cognitive performance as we age.
Dr. Kennedy's currently funded research project involves investigating the role of white matter in the reorganization of age-related brain function using structural and functional imaging techniques. She is interested in understanding how the brain changes with age, both adaptively, and detrimentally, and how this knowledge might be used to stave off cognitive decline.
Keywords: neural, genetic, and lifestyle factors that affect normal aging, brain mapping, white matter, MRI techniques, age-related brain reorganization
Rieck, J. R., Rodrigue, K. M., Boylan, M. A., Kennedy, K. M. (2017). Age-related Reduction of BOLD Modulation to Cognitive Difficulty Predicts Poorer Task Accuracy and Poorer Fluid Reasoning Ability. NeuroImage, 147, 262-271. http://dx.doi.org/10.1016/j.neuroimage.2016.12.022
Kennedy, K. M., Rieck, J. R., Boylan, M. A., Rodrigue, K. M. (2017). Functional magnetic resonance imaging data of incremental increases in visuo-spatial difficulty in a large adult lifespan sample. Data in Brief, 11, 54-60. http://dx.doi.org/10.1016/j.dib.2017.01.004
Kennedy, K. M., Reese, E., Horn, M., Sizemore, A., Unni, A., Meerbrey, M., Kalich, A., Rodrigue, K. M. (2015). BDNF val66met Polymorphism Affects Aging of Multiple Types of Memory. Brain Research, 1612(0), 104-117. http://dx.doi.org/10.1016/j.brainres.2014.09.044
Kennedy, K. M., Rodrigue, K. M., Bischof, G. N., Hebrank, A. C., Reuter-Lorenz, P. A., & Park, D. C. (2015). Age trajectories of functional activation under conditions of low and high processing demands: an adult lifespan fMRI study of the aging brain. NeuroImage, 104, 21-34. http://dx.doi.org/10.1016/j.neuroimage.2014.09.056